Plasmodium vivax


Virtual Microscope

Ring

Ring

- Delicate ring

- RBC larger than normal

- Deformed

Growing trophozoite; Schüffner's dots

Growing trophozoite; Schüffner's dots

- Very amoeboid trophozoite

- Enlarged RBCs and deformed

- Schüffner's dots appear after 8-10 hours

Immature schizont

Immature schizont

- Looks like a growing trophozoite with several chromatins

- The single merozoite is not yet defined

Mature schizont

Mature schizont

- Contains 12-24 merozoites

- Pigment in 1 or 2 clumps

- Peripheral or central

Ruptured schizont

Ruptured schizont

- RBCs membran ruptured and the merozoites (up to 24) are set free to infect new RBCs

Macrogametocyte

Macrogametocyte

- Chromatin small

  • Eccentric and dark red

- Cytoplasm homogeneous

  • Blue
  • Without vacuoles
  • Pigment scattered

- Macrogametocyte fills the RBC

Microgametocyte

Microgametocyte

- Chromatin mass larger than in microgametocyte

  • Eccentric or central
  • Diffuse
  • Light red

Cytoplasm from light blue to pink

  • Pigment finer
  • Scattered

- Microgametocyte is smaller than the RBC

Exflagellation

Exflagellation 

- Under certain circumstances the microgametocyte of P. vivax can exflagellate in a thin film of human blood

- A process that normally takes place in the vector's gut

- There the microgamete (male) undergo a nuclear division and become motile to find and to penetrate the female macrogamete